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2 , 7 , 28 The results from this indirect treatment comparison showed a mean difference in percent bodyweight reduction between tirzepatide 15 mg and semaglutide 2.4 mg ranging from 4.4% to 5.3%, with up to 2.2 times greater odds of achieving 5% weight reduction
"The usual safety precautions have been bypassed, in one way or another, and this increases the medical risk of using such a product." Dumont noted there's a good reason prescription drugs are tightly regulated, from the FDA approval process to how they are manufactured and prescribed

Diabetes, Obesity & Metabolism, 25(4), 961964

Emotional experiences and past trauma has wired our brains to believe we need to eat when we arent even hungry

Managing these effects successfully requires understanding the complete GLP-1 medications treatment process, including when to adjust doses, what symptoms require medical attention, and how to optimize nutrition during the adjustment period

A 2024 study found an increased risk of heart attack and stroke among people who used cannabis just once a week, and those odds rose with more frequent use
