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We examined temporal trends in annual initiation prevalence

GLP-1 agonists have emerged as promising therapeutic agents for diabetic cardiomyopathy through multiple protective mechanisms

[5] The SURMOUNT-4 trial showed similar patterns for tirzepatide: patients switched from the drug to placebo regained about 14% of body weight over the following year, effectively erasing most of their loss

S.Van WittenbergheN.EricssonM.GriffinG

Statistical analyses Statistical analysis of the cognitive tests was performed using Prism (Prism 8 for MacOS, Graphpad, LCC, Version 8.4.0 (455))

Also, because GLP-1 drugs engage the brain's reward circuitry the same system that governs not just craving but everyday motivation prolonged use could, in theory, dampen motivational drive in some people