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643828 Prokhorov AV, Hudmon KS, Stancic N (2003) Paediatr Drugs 5:110 Pryor WA, Stone K, Zang LY et al (1998) Chem Res Toxicol 11:441448 Richter E, Engl J, Friesenegger S et al (2009) Chem Res Toxicol 22:10081017 Rodgman A, Perfetti T (2009) The Chemical Components of Tobacco and Tobacco Smoke

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Selective elimination of senescent cells reversed atherosclerosis, enhanced stability and improved vulnerability of atherosclerotic plaques, reduced fibrosis, alleviated cardiomyocyte hypertrophy, and increased heart regenerative capacity [14,15,16]