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This despite the fact that the use of alternative and substitute methods to animal testing has been envisaged for some time also for alcohol, tobacco and other drugs
(such as TTB permits) and potentially state-level permits as well

Druckerman said

and Piha, T., 1994
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While GnRHa is not an OC, it changes sex-hormone levels and could provide additional information on the effect of changes in sex-hormone levels on reward processing