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This approach may be more widely useful as a conformational sensor for other GPCRs, although it lacks the ability to detect changes at the receptor intracellular face that are needed to provide insights into conformational changes required for G protein interactions

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Uno de los problemas persistentes y relevantes en la medicina clnica es el ndice de masa corporal (IMC) excesivo de los pacientes, principalmente debido a la acumulacin excesiva (aumento en tamao y volumen) de tejido adiposo, comnmente conocido como obesidad

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