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Beyond standard cytokines, adipose tissue secretes specialized signaling proteins called adipokines, which regulate systemic inflammation, metabolism, and immune responses, thus contributing to HS development and progression [7, 8]

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*Clinical studies show patients treated with GLP-1s experienced an average weight loss of 14.9-20.9% of their total body weight after 68-72 weeks

Individualized riskbenefit assessment and clinical monitoring are warranted, particularly in vulnerable populations or those with complex psychiatric comorbidities

The Caloric Floor There is a minimum calorie intake below which recovery becomes meaningfully impaired regardless of how well you structure everything else