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Common Side Effects and Management Strategies Nausea is the most frequently reported side effect when starting semaglutide, affecting 20-40% of patients in early phases

This kind of monitoring is especially important for people over 65 years old, those with diabetes, and people taking several medications

Improve your sleep hygiene if youre waking up tired

Fatigue is almost always temporary and resolve within 2-8 weeks as your body adapts

The most common side effects are digestive and may include nausea, constipation, diarrhea, vomiting, reflux, decreased appetite, or abdominal discomfort