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GLP-1 receptor agonists mimic endogenous incretin hormones to regulate glucose levels and induce satiety

Muscle protein synthesis depends on two primary signals: Mechanical stimulus , usually provided through resistance training Amino acid availability , primarily from adequate dietary protein Resistance training activates the pathways responsible for muscle repair and growth, while dietary protein provides the amino acids required for rebuilding muscle tissue

The study also found that adults taking a GLP-1 had an increased risk for interstitial nephritis, a type of kidney condition that Al-Aly says is almost like an allergic reaction that the kidney mounts against certain drugs. He says more long-term studies are needed to better understand the risks and benefits of prolonged use

doi:10.1111/jdi.12450 59

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Liraglutide, initiated at 0.6 mg per day, was escalated to the maximum tolerated dose or up to 3.0 mg per day over 4 weeks