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J Endocrinol 2014;221(1):T116

Although GLP-1 medications are highly effective for obesity treatment, disregarding sexual health and desire as an essential consideration in initiation of GLP-1 agonist therapy presents a serious concern

Although a modest increase in psoriasis incidence was observed, the absolute risk remained low and should be interpreted in the context of the well-established cardiometabolic benefits of GLP-1 RAs

Whether there is a real impact of GLP-1 drugs on cancer is unresolved

Adding a third receptor target could theoretically create more adverse effects, but the clinical data shows comparable or even improved tolerability versus Semaglutide

STAT News cited a recently published British Medical Journal review of 37 studies, tallying an aggregate of more than 9,300 participants, in which approximately 50% of the people who started on the drugs stop taking them within one year