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Gallstones and Gallbladder Disease Rapid weight loss, especially more than 1% of body weight per week, can increase the risk of gallstone formation by changing how bile is made and released

The DQSA was not in place during the Makena action, and the new law never intended that the FDA would weigh drug prices in allowing compounded medicines

These findings are consistent with data accessed October 10, 2025

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It must be used as an adjunct to a reduced-calorie diet and increased physical activity