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In humans, GLP-1 is not only damaged by DPP-4, but also by neutral endopeptidase 24.11 (NEP 24.11), and the main catalytic sites are Glu 27 Phe 28 and Trp 31 Leu 32

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Triple hormone receptor agonist retatrutide for metabolic dysfunction-associated steatotic liver disease: A randomized phase 2a trial

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