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Semaglutide reduced the leukocyte recruitment by the downregulation of IL-6, IL-1RN, and chemokine (C-C motif) ligand 2 (CCL2) gene expression

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Unlike hormone replacement therapy, which directly replaces estrogen, semaglutide works on neural pathways independent of hormone levels, making it effective during menopause even when estrogen cannot be restored

Avoid tight clothing over the injection site for at least an hour to prevent friction and additional irritation

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