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Glimepiride in Type 2 Diabetes) with linagliptin comparing linagliptin treatment as add on to metformin directly with a therapy with the sulfonylurea glimepiride will bring results later in 2019 and may give additional insights into the association and mechanisms linking hypoglycaemic- with cardiovascular events (24, 69)

The findings showed the most consistent risks involved gastrointestinal issues, with roughly double the likelihood of nausea, vomiting and diarrhea

Belcher denied these claims

DPP4 activity was assessed using fluorometric assay (substrate: 10 mM H-Gly-Pro-AMC HBr, Bachem catalog I-1225