retatrutide benefits besides weight loss vs. Tirzepatide: The New Contender vs. the Current Leader Retatrutide Peptide Weight Loss Therapy
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doi: 10.14670/HH-13.169

If cardiovascular outcomes of tirzepatide are similar to GLP-1 RAs, the medication may be used by practitioners preferentially prior to using GLP-1 RAs in patients with or without diabetes who desire weight-loss
Serious adverse events such as cardiac disorders, atrial fibrillation, and cardiac failure were more common in the placebo group than in the semaglutide group, indicating beneficial hemodynamic effects [38]

Packer 2023)

Constipation-predominant IBS was linked to lower mucosal expression of GLP-1 receptors and serum GLP-1 concentrations (25, 26)
