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Jessica K Walker, University of Birmingham, Institute of Metabolism and Systems Research, Birmingham, B15 2TT, UK
however, whether GLP-1Rpositive, leptin receptornegative neurons in the DMH are critical for the chronic effects of GLP-1RA treatment has not been examined
Nevertheless, ongoing research and development in this field are paving the way for more potent, targeted, and accessible therapies
An alternative approach aiming to maximize the efficacy of GLP-1 involves the delivery of nuclear receptor agonists to specific tissues characterized by the expression of GLP-1R
