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In parallel, systematic evaluation of how genetic polymorphisms, environmental exposures, divergent metabolic stressors, variable susceptibility to hepatocyte lipotoxicity, and differences in tissue-repair capacity shape the actions of these drugs will be crucial for advancing truly personalized therapy [53]
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Key lifestyle changes, including dietary adjustments, increased physical activity, and behavioural therapy, are foundational to obesity management
When reimbursement expands, as in the earlier example of the NHS agreement for Mounjaro, an even wider group of doctors, in particular general practitioners (GPs), will be exposed to AOMs as prescribers
P.GholamiS.et al (2019)
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