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Additionally, GLP-1 can inhibit apoptosis by activating the PI3K/Akt pathway, promoting the anti-apoptotic protein Bcl-2 and hindering the activity of caspases

doi: 10.1111/dom.16243

Taking metformin with meals can further reduce side effects

Psoriatic Arthritis Treated with Liraglutide Therapy: A Quality of Life and Efficacy Study (Plaque)

A thorough discussion of your personal medical history with your doctor is crucial before starting any GLP-1 RA therapy

However, there are still questions around P9s mechanism, whether it's present in other bacterial species and whether it influences the secretion of other gut hormones, such as GLP-2 and peptide YY