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Supplementation with B12 or methylcobalamin can produce noticeable energy improvements within one to two weeks if deficiency is present

Gut Microbes 2023;15:2274124
[DOI] [PubMed] [Google Scholar] 55.Li ZY, Zhang N, Wen S, Zhang J, Sun XL, Fan XM, et al

Potential benefits could include reduced need for revision surgeries, lower readmission rates and fewer post-operative infections
Patients with treatment-resistant depression and obesity
And unlike other tissues, nerves dont heal well, so the damage is often permanent
