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Findings thus far have been translated into recommendations in clinical guidelines by the American College of Cardiology, American Heart Association, European Society of Cardiology, and American Diabetes Association

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Arrestins act as scaffolds to promote recruitment and activation of mitogen-activated protein kinases (MAPKs) that are linked to protection against apoptosis and pancreatic beta-cell survival and growth [35]

It is significantly boosting the risk of diabetes development

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Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38