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GLP-1 has a short half-life (around 2 min), due to the action of the enzyme dipeptidyl-peptidase-4 (DPP-4), a serine aminopeptidase, and because of renal clearance, due to its low molecular weight
Licensed versus unlicensed prescribing Switching for non-formulary or intolerance reasons may constitute off-label use
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At the concentrations used in compounded semaglutide, it contributes minimal visible color on its own
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