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For example, the RNA sequencing analysis on isolated enteroendocrine cells from obese individuals with or without T2DM revealed decreased expression of the PCSK1 gene in the jejunal epithelium, contributing to the biosynthesis of GLP-1 [32]

This risk seems to be highest in young people and women

Chereddi is clear about where the format battle ultimately ends: "Oral drugs will surpass injectables, and global data already supports the trend

GLP-1 receptor agonist therapy requires ongoing assessment and potential dose adjustments based on treatment response, tolerability, and evolving clinical needs

exenatide's shorter half-life)

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