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[6] [7] This delayed emptying creates a sensation of fullness that contributes to weight loss but can also trigger nausea, particularly when the stomach remains distended

Visceral adiposity, insulin resistance, inflammation

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Tirzepatide cardiovascular event risk assessment: a pre-specified meta-analysis

The work suggests that astrocytes and glial peptides like DBI/ODN are active participants in the GLP-1 pathway, shaping appetite suppression and offering potential as new therapeutic targets

2025 Aug;7(8):1536-1549
