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Incretin receptor agonists, including tirzepatide, may potentially increase the risk of thyroid C-cell tumors based on findings in animal studies

Its Phase 3 trials have produced about 28% average weight loss

[Link] Garsed K, Chernova J, Hastings M, et al
SURMOUNT-1 reported mean weight loss approaching 20% at the highest dose

Semaglutide can reduce thirst signals, but dehydration worsens nausea and reduces energy
