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Novel GLP-1R Agonists in Neurotherapeutics NLY01 is a pegylated, long-acting GLP-1 receptor agonist designed with a unique peptide sequence that facilitates blood-brain barrier penetration and sustained brain exposure

GLP-1 meds help people lose significant amounts of weight, reduce their risk of heart disease, stroke, type 2 diabetes, and countless other obesity-related conditions, and in many cases, even reverse metabolic dysfunction

doi: 10.1002/ptr.3621

Some studies have observed synergistic effects of dual GLP-1R and GIPR agonism on glucose tolerance, insulin secretion, body weight and food intake in mice [113,114,115]

For patients with high risk of developing NAION (eg, those with diabetes or hypertension) who are taking GLP-1 receptor agonists, ophthalmologists may increase vigilance. The researchers concluded that further research is warranted to replicate these findings, explore underlying mechanisms, identify individuals at increased risk for these potential complications and examine other eye disorders. Diabetic retinopathy In another analysis, David J
