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2022;34(9):1234e12479

If you still cannot tolerate the maintenance dose of 2.4 mg once weekly, speak with your healthcare professional about decreasing the maintenance dose to 1.7 mg once a week

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If glucose or weight-loss goals are not met on one GLP-1 agent at a therapeutic dose, the evidence-based approach is to optimize that single drug (titrate to effective dose, extend time on therapy) or switch to a different class entirelysuch as combining a GLP-1 with a SGLT2 inhibitor or adding metforminrather than stacking two GLP-1s

D1-Dopamine Receptor Availability in First-Episode Neuroleptic Naive Psychosis Patients

But here is the difference that matters