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[DOI] [PMC free article] [PubMed] 82.Dun Y, Smith JR, Liu S, et al

Ghrelin and glucagon-like peptide 1 concentrations, 24-h satiety, and energy and substrate metabolism during a high-protein diet and measured in a respiration chamber

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However, potential side effects of branded GLP-1s are well-documented and must be disclosed according to FDA regulations
Overall, while semaglutide and tirzepatide remain effective options, mazdutide may offer enhanced metabolic benefits through its combination of appetite suppression, energy expenditure, and targeted fat loss, making it a promising candidate for patients with obesity complicated by metabolic disorders

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