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Inform patients of the signs and symptoms of acute kidney injury and instruct them to promptly report any of these signs or symptoms or persistent (or extended) nausea, vomiting, and diarrhea to their healthcare provider [see Warnings and Precautions (5.5)]

This is a normal and expected response, not a side effect to be concerned about

The hair follicles shift from growth phase to resting phase synchronously, leading to increased shedding
Its certainly at least mostly a blood pressure effect

However, they are not prescribed alone for bipolar disorder

A meta-analysis of epidemiological studies revealed a higher incidence of inflammatory bowel disease in males, with a male-to-female ratio of 1.64:1 for Crohns disease and 1.29:1 for ulcerative colitis [64]