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Lancet 375:14471456 Mannucci E, Ognibene A, Cremasco F et al (2001) Effect of metformin on glucagon-like peptide 1 (GLP-1) and leptin levels in obese nondiabetic subjects

One-eighth of this weight loss is dropped in the first month of treatment

Even gentle carbs like oatmeal will provide nutrients such as fiber and some vitamins and minerals

It is part of a class of drugs known as glucagon-like peptide-1 receptor agonists (GLP-1 RAs)

Novo Nordisk Pharma and Sumitomo Pharma have been jointly promoting Ozempic since July 2025, under the co-promotion agreement for the type 2 diabetes treatment Ozempic

Image credit: Matt Fowler KC/Shutterstock.com Glucagon-like peptide-1 receptor agonists (GLP-1RAs) can produce significant weight loss in obese individuals