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In the SURMOUNT-1 trial, participants on the highest dose lost an average of 22.5% of their body weight over 72 weeks, with over half achieving at least 20% weight loss

Recent developments and formulations are summarized in Table 1C

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These agonists, e.g., Resmetirom, have been employed in ongoing studies and have demonstrated a favorable impact on NAFLD [42]

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