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The most common side effects are GI symptoms such as nausea, diarrhea, constipation, headache, fatigue, decreased appetite, and/or dizziness, most often due to low blood sugar (hypoglycemia)

In addition, differences in the initial situation of gastric emptying, which is a measure of the effectiveness of GLP- 1- receptor co-agonists, are likely to have a different effect on patients with obesity than on people in whom preoperative intragastric food retention after taking GLP- 1 receptor co-agonists is not impaired, and in people with diabetes [127]

YesPlexusDx provides digital dose tracking in your patient portal, refill reminders, and coordination with your care team to optimize injection timing

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Once opened or prepared for use, semaglutide typically maintains potency for 28 days when stored correctly under refrigeration

Clinical trials demonstrate that combining GLP-1 receptor agonists with insulin leads to greater A1C reductions than either drug alone