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This study was an observational cohort investigation using electronic health record data from the United States Department of Veterans Affairs and included 606,434 patients with type 2 diabetes who newly started either a GLP-1 medication or, as a comparator, a sodium-glucose cotransporter-2 inhibitor (a type 2 diabetes medication that doesnt affect appetite and reward pathways) based on filled outpatient pharmacy records

Testosterone, by contrast, is a well-established, licensed therapy used for confirmed hypogonadism and gender-affirming care under specialist supervision

UACR: microalbumin/creatinine in urine

Summer repeatedly emphasizes that these medications exist within a much bigger picture that includes medical history, lived experience, mental health, access to care, and individual goals

They also calm inflammation , a hidden trigger for many chronic illnesses, including heart disease, fatty liver, and metabolic syndrome

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