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Metformin mitigates amyloid 1-40-induced cognitive decline via attenuation of oxidative/nitrosative stress and neuroinflammation
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DHEA indirectly increases levels of type 2 11-HSD, causing greater conversion of glucocorticoids to the inactive state and decreasing overall glucocorticoid activity (Balazs 2008)

Hankosky ER, Wang H, Neff LM, et al
Malzahn (Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, UK) for providing the picture of the histology slide in Fig
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Two recent reviews make this clear
