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doi: 10.1126/science.aau2277

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Scenario 2: Managing Side Effects Lets be honest, side effects like nausea can happen, especially during the initial titration phase

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GLP-1 agonists (Semaglutide, Tirzepatide) These FDA-approved medications have longer shelf life data

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Other incretin projects : Lilly acquired Protomer Technologies in late 2024 specifically to get access to novel glucagon/GLP-1 peptides and oral incretins

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For the current retatrutide trial status and latest monthly updates, see our current approval status and latest trial updates

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