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NBC News' Berkeley Lovelace Jr

Berberine and GLP-1 are fundamentally different compounds targeting distinct metabolic pathways
The framework prioritised semaglutide and tirzepatide as first-line treatments, based on evidence of 15% weight loss and benefits in complications such as cardiovascular disease and sleep apnoea

Two major ongoing trials are likely to change that, with potentially big implications for clinical practice.

GLP-1 receptor agonists ((GLP-1 RAs) are currently receiving a lot of attention because of their impact in diabetes, weight loss and other areas
