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Thank you, VITAstir, for helping me reclaim my life and confidence! Anna Bula 2018 SUMMER WEIGHT LOSS CHALLENGE WINNER

Specifically, loss of function variants identified in Nicastrin (NCSTN), Presenilin Enhancer 2 (PSENEN2), Presenilin 1 (PSEN1), Aph-1A and Aph-1B Gamma-Secretase Subunits (APH1A and APH1B) genes, lead to haplo-insufficiency that ultimately results in defective Notch signaling [46,47,48,49,50]

After symptoms resolve, a slower re-escalation can be attempted, perhaps increasing by smaller increments than the standard protocol specifies

In these cases, nutrient support can be incredibly helpful

One important distinction
