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It is important to keep in mind that we need larger randomised clinical trials to confirm these findings, Leggio said.

549 The reactive astrocytes can promote excitotoxic injury of motor neurons by producing nitric oxide and peroxynitrite, which cause mitochondrial damage and apoptosis in cultured neurons, decreasing glutamate transport, releasing pro-apoptotic mediators selectively toxic to motor neurons

According to the company's website, more than 100,000 patients have started a GLP-1 journey through the platform

Why Tirzepatide Starts at 2.5 mg Many patients wonder why treatment does not begin at 5 mg or a higher dose

Contact your healthcare provider for further evaluation if you experience severe abdominal pain, fever, clay-colored stools, or yellowing of your skin or whites of your eyes
The dose is always quoted per side, and both sides are treated unless there is a specific reason to treat asymmetrically
