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healthcare will play an increasing role in shaping the future of care delivery, particularly as payers, especially employers, reassess the cost-effectiveness of pharmaceutical interventions relative to traditional medical procedures

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Acknowledgments The authors did not receive any funding or sponsorship for the publication of this article

Blood was collected via a jugular vein catheter at 5, 15 and 30 min and 1, 2, 4, 8 and 24 h after intravenous dosing, or for intraduodenal groups at 15 min predose and 0.5, 1, 2, 4, 8, 24 and 48 h postdose