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Description
The SURMOUNT-5 trial (Aronne et al., NEJM 2025) showed that tirzepatide, a dual GIPGLP-1 receptor agonist, outperforms semaglutide in reducing weight and cardiometabolic risk in adults with obesity without diabetes
The OASIS 4 trial evaluated the safety and effectiveness of once-daily semaglutide25 mgin obese and overweight patients without T2DM
Learn about their causes and when to see a doctor here.
Tirzepatide vs semaglutide UK: compare mechanism, STEP trial data, dosing protocols, and 99% HPLC-verified sourcing for researchers
Important: These drugs are not for everyone and must be prescribed and monitored by a clinician
These medications have many benefits, including cardiovascular and renal protection, blood pressure reduction, and improvements in glucose levels
