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Exendin-4 relieves the inhibitory effects of high glucose on the proliferation and osteoblastic differentiation of periodontal ligament stem cells

The research findings require validation through longitudinal studies, since GLP-1RAs might modify immune pathways in ways that could intensify inflammation for some people [51]

In addition, -lipoic acid has also been reported to have beneficial effects on diabetic neuropathy, although whether AMPK is also involved in mediating these effects is unknown

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