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This may have been the main impetus of Novos decision not to make the payment and allow the particular patent to lapse, likely not an oversight. In this view, letting the patent lapse might have simply been a low-cost calculation, especially if Novo believed their core IP protection was set to expire soon

Over a year, that 60-100 calorie daily deficit represents 6-10 pounds of potential weight loss or, conversely, 6-10 pounds of easier weight regain during a drug holiday

[DOI] [PMC free article] [PubMed] [Google Scholar] 32.Meier J.J., Nauck M.A

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