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Glp1r / mice, and, to a greater extent, Glp1r / : Gipr / mice, exhibit defective glucose-stimulated insulin secretion, subnormal upregulation of insulin gene expression in response to high-fat diet (HFD) feeding, and impaired glucose tolerance (3, 4)

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Updated January 13, 2026

If you have high thyroid antibody levels but normal thyroid function tests (TSH and Free T4), you do not require treatment with thyroid hormone

Wegovy produced average weight reductions of 14.9% over 68 weeks in the STEP 1 trial and 15.2% in STEP 5

Medications are prescribed only when medically appropriate, and we do not continue prescriptions outside our clinical judgment or scope