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Accordingly, a retrospective analysis of SUSTAIN-6 examined the role of preexisting advanced retinopathy and the induction of rapid reductions in plasma glucose and HbA 1c and found retinopathy complications mainly in those with preproliferative or proliferative retinopathy at baseline who experienced a large reduction in HbA 1c within 16 weeks after initiation of semaglutide (83)

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Switching between medications If one medication becomes unaffordable but another remains accessible, switching may be viable

Extended use would require a comprehensive dialogue with the patient

doi: 10.1097/00004872-200306000-00012 94 KatsuradaKNakataMSaitoTZhangBMaejimaYNandiSSet al

The glucagon component is what truly sets retatrutide apart from everything else in the pipeline
