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Disclosures Andr J

Bi-weekly injection schedules create peaks and troughs in medication concentration, potentially reducing appetite suppression during the second week and diminishing overall weight loss effectiveness

Losing weight often involves losing some muscle along with fat, and since muscle burns more calories than fat, your daily energy expenditure drops further

She says the telehealth companies can be useful, but they also offer employers "utilization management under the guise of lifestyle intervention." "The endgame is to eventually get the patient healthy, get them on an exercise program and get them off the GLP-1s," she says

These devices deliver energy waves to the deeper layer of the skin

In December 2025, the Food and Drug Administration (FDA) approved an oral pill form of Wegovy for weight loss, and in April 2026 approved the once-daily oral GLP-1 drug Foundayo (orforglipron) also for weight loss