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This feeling is actually controlled not by the gut but by the brain, which also has GLP-1 receptors

Key Takeaways GLP-1 (glucagon-like peptide-1) is produced in your gut after eating and signals your brain that you're full

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This approach is particularly helpful for people with injection anxiety or needle sensitivity

They are optimal for their insulinotropic effect exclusively when glucose levels are elevated, thereby providing the capacity to decrease plasma glucose while mitigating the risk of hypoglycemia