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Pramlintide as an adjunct therapy in patients with type 2 diabetes
In diabetes, the emphasis may be on glycemic monitoring and integration with other medications
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GLP-1 acts through a class 2 member of the G-coupled protein C receptor family seven-transmembrane receptor (GLP-1R) (8), which is mainly expressed in pancreatic islets, the brain, and the gastrointestinal (GI) tract (912), and less prominently in the kidney and eyes (1113)
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In clinical trials, tirzepatide demonstrated significant reductions in hemoglobin A1c (up to 2.5% reduction) in patients with type 2 diabetes
