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For tirzepatide (Zepbound) Jastreboff and colleagues reported in the New England Journal of Medicine in 2022 that at maximal doses, the percent of individuals reporting side effects were as follows: Nausea 31.0% Diarrhea 23.0% Vomiting 12.2% Constipation 11.7% Bettge and colleagues conducted a study published in Diabetes, Obesity, and Metabolism in 2017 that showed that individuals who were taking metformin while taking a GLP-1 were more likely to have side effects, especially nausea and vomiting

However, the fact that it is a common and even expected circumstance doesnt make it any less frustrating for the patient who stops losing weight before they have reached their goal

10.1016/S1474-4422(12)70142-4 19 ConnollyB

The impact of diabetes on breast cancer treatments and outcomes: a population-based study

Why Does Hypoglycaemia Happen on GLP-1s

What side effects should I expect on tirzepatide