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In another study, people who paired semaglutide with a structured lifestyle program lost slightly more during treatment and regained less afterward

However, one study used a guessing task involving monetary rewards instead of food rewards, and the final reward received by the participants did not depend on wins and losses during the task, thereby rendering the choices during the task hypothetical which might not resemble tasks that assess anticipatory or consummatory reward facets more directly (Bogdanov et al., 2020)

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There are rare but significant conditions that can mimic the feeling of a leg cramp
