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(b) stimulation of the AMPKSREBP-1cSCD1 pathway diminishes hepatic steatosis and triglyceride (TG) accumulation [120]

In addition, stimulation of GLP-1R exhibits antioxidant and antiapoptotic effects as well as the improvement of mitochondrial functions through cAMP/Epac/PI3K/Akt signaling pathway in H9c2 cells

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Cells were incubated with serum-free media for 24 h prior to each experiment and seeded at 1 10 6 cells/dish in 100 mm culture dishes for western blotting and 3 10 4 cells/well in 24-well- culture plates for immunofluorescence