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In simpler terms, each heartbeat pushes more blood with more force

Diabetes Care 33(2):428433 Eguchi Y, Kitajima Y, Hyogo H, Takahashi H, Kojima M, Ono M et al (2015) Pilot study of liraglutide effects in non-alcoholic steatohepatitis and non-alcoholic fatty liver disease with glucose intolerance in Japanese patients (LEAN-J)

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BMI requirements for GLP-1 qualification vary by medication and indication, but many adults with obesity or overweight with comorbidities qualify

However, digestive side effects can stack, particularly nausea and bloating
