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More than half a billion people are living with diabetes worldwide and it is estimated that by 2045 there will be 693 million people diagnosed with the condition [1]

Moreover, the clinical significance of lean mass loss cannot be inferred solely from quantitative measures, as muscle quality, strength, and metabolic function may be preserved or even improved in some contexts [15,16,17]

Patel S

This may be partly mediated by improvements in weight loss and glucose control

Once diagnosed, assessment and management should address reproductive, metabolic, cardiovascular, dermatologic, sleep, and psychological features